Lentigo maligna

By Dr. Vishaal Bhat on Tuesday, November 6, 2007 with 0 comments

Lentigo maligna (melanosis circumscripta praeblastomatosa) forms dotted pigmentation and indistinctly bordered foci on the face skin exposed to the solar radiation. It may also appear on the oral mucosa of lips, gingiva and palate.

Histological picture shows hyperpigmentation of basal melanocytes at early stages, which can later form clusters of melanocytes. This proliferation of the population of melanocytes determines atrophy of the epidermis, under which a strong inflammation of the stroma is apparent.

Early diagnosis of lentigo maligna and its differentiation from benign melanoses (pigmented nevi) is crucial, a timely excision guarantees almost 100% success of therapy. Otherwise almost 50% of lentigo maligna cases get transformed into a malignant melanoma.

Category: Featured , Stomatology Notes



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