Chaperons

By Dr. Vishaal Bhat on Tuesday 20 July 2010 with 0 comments



These are heat shock proteins that facilitate and favour the interactions on the polypeptide surfaces to give the specific conformation of a protein. They also help the protein to attain compact and biologically active conformation.

The failure of protein to fold properly leads to its rapid degradation. The misfolded proteins are called prions . Sometimes these prions accumulate in the cells and cause neurological diseases like Alzheimer’s disease.

Category: Biochemistry Notes , Genetics Notes , Pathology Notes

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