Adenoid Cystic Carcinoma

By Dr. Vishaal Bhat on Tuesday 1 January 2008 with 0 comments



  • Account for 3-10% of salivary gland tumours— more common in minor salivary glands

  • Twenty-five percent arise in major salivary glands, most commonly the submandibular

  • May arise at any age, but occur most frequently in the 4th to 6th decades

  • Patients with tumours in the major glands commonly present with a painful mass. Those in the minor glands can also produce respiratory obstruction

  • Usually form well-defined masses, but histologically are seen to infiltrate surrounding tissues

  • Perineural invasion is characteristic of this neoplasm, and this feature seems to account for the poor long-term outcome in patients with this tumour.

  • Metastasis can occur to cervical lymph nodes or distant sites e.g. lung, bone, liver, brain

  • 5-year survival rates as high as 70% have been reported, but rate declines to 5-15% at 20 years.

Category: Oral Pathology Notes

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